Episomal expression cassettes for gene therapy
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United States of America Patent
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Apr 16, 2002
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N/A
app pub date -
Nov 12, 1999
filing date -
May 14, 1997
priority date (Note) -
Expired
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Abstract
The invention consists of episomal expression cassettes for expression of a transgene in gene therapy. The expression cassettes consist of regulatory elements of the human cytokeratin gene and a transgene. The invention also includes of liposomes for transfection of epithelial tissue with the cassettes in treatment of cystic fibrosis, emphysema, cancers of epithelial origin arising in the lung or other organs.
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