Substituted 1,3-oxathiolanes with antiviral properties
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United States of America Patent
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Apr 9, 2002
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app pub date -
Nov 28, 2000
filing date -
Nov 13, 1990
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Abstract
This invention relates to single enantiomers of novel cis-substituted 1,3-oxathiolanes, of the formula (I): ##STR1## wherein; R.sub.1 is hydrogen, and R.sub.2 is cytosine or 5-fluorocytosine; and pharmaceutically acceptable salts and esters thereof. This invention also relates to pharmaceutical compositions containing them and to the use of these compounds as antiviral agents, particularly in combination therapy.
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