Assay for asymmetrical NG, NG dimethyl-l-arginine
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United States of America Patent
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Mar 19, 2002
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app pub date -
Feb 1, 2000
filing date -
Feb 5, 1999
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Abstract
ADMA is determined in a physiological sample by first removing interfering components: proteins by precipitation; and amines and citrulline, by means of a cation exchange column, followed by enzymatic hydrolysis of the ADMA to citrulline with DDAH. The citrulline is then determined spectrophotometrically.
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