Optical resolution of narwedine-type compounds
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Feb 12, 2002
Grant Date -
N/A
app pub date -
Jun 28, 1999
filing date -
May 24, 1996
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A process for the asymmetric transformation of a racemic compound of formula (I) wherein R.sub.1 is H or a alkyl group having up to 20 carbon atoms, R.sub.2 is H, or an alkyl, aryl, alkaryl or aralkyl group having up to 20 carbon atoms, and X is H, a halogen atom, tert-butyl, or any other removable substituent, comprises reaction of racemic compound (I) with an enantiomerically-enriched acid HY*, wherein Y* is a chiral group, to form a diastereomeric salt of compound (I) having Y* as a counterion. The salt obtained can then be reduced to give enantiomerically-enriched galanthamine, or a derivative thereof. ##STR1##
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully