Method for producing human hemoglobin proteins using plant cells

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United States of America Patent

PATENT NO 6344600
SERIAL NO

08983564

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Abstract

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A method for producing human hemoglobin proteins by (i) inserting into plant cells one or more nucleic acid molecules that each comprise at least one sequence coding for a protein component of a human hemoglobin protein capable of reversibly binding oxygen, and optionally a sequence coding for a selection agent; (ii) selecting cells containing nucleic acid coding for the protein component of the human hemoglobin protein; (iii) optionally propagating the transformed cells either in a culture or by regenerating whole transgenic or chimeric plants; and (iv) recovering and optionally purifying the human hemoglobin protein that includes a complex consisting of the protein or proteins coded for by the nucleic acid and at least one iron-containing polphyritic nucleus, or a plurality of such complexes.

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Patent Owner(s)

Patent OwnerAddress
MERISTEM THERAPEUTICS8 RUE DES FRERES LUMIERE CLERMONT-FERRAND 63100

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Baudino, Sylvie Orcines, FR 4 33
Dieryck, Wilfrid Saint-Pathus, FR 2 31
Gruber, Veronique Chamalieres, FR 15 127
Lenee, Philippe Noumea, FR 7 35
Marden, Michael Aulnay-sous-Bois, FR 5 23
Merot, Bertrand Volvic, FR 9 126
Pagnier, Renee-Josee Le Kremlin-Bicetre, FR 2 22
Poyart, Claude Paris, FR 3 35

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