Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment

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United States of America Patent

PATENT NO 6342531
SERIAL NO

09646529

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Abstract

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A pharmaceutical composition for the prophylaxis and therapy of brain tissue impairment, which contains, as an active ingredient, a compound of the following formula (I) ##STR1## wherein R.sup.1 represents an alkyl group having 1-4 carbon atoms or an aryl group having 6-10 carbon atoms which is optionally substituted; R.sup.2 and R.sup.3 may be the same or different and each represents hydrogen or an alkyl group having 1-4 carbon atoms or R.sup.2 and R.sup.3 may jointly form a ring having 3-7 carbon atoms; and R.sup.4 represents a lower alkyl group which is optionally substituted by aryl, cycloalkyl, or aromatic heterocyclic residue, or a pharmaceutically acceptable salt thereof.

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Patent Owner(s)

Patent OwnerAddress
SENIU PHARMACEUTICAL CO LTD5-8 HIRANOMACHI 2-CHOME CHUO-KU OSAKA-SHI OSAKA 541-0046

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Azuma, Mitsuyoshi Nishinomiya, JP 23 107
Inoue, Jun Kobe, JP 81 1171
Sakamoto, Yuji Kobe, JP 64 2269
Yoshida, Yukuo Kobe, JP 7 65

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