Radiation enhanced gene therapy for tumors expressing a gene for a viral pyrimidine kinase in the presence of a 5'-halogenated pyrimidine

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United States of America Patent

PATENT NO 6342217
SERIAL NO

09358597

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention pertains to combination radio therapy of tumors and more specifically to pharmaceutical compositions, and methods of treatment by gene therapy designed to sensitize tumors in animals, notably humans, and render them more susceptible to radiation, thus significantly reducing the amount of radiation required to kill neoplastic cells while at the same time making the radiation far more tissue specific to the tumor site.

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Patent Owner(s)

Patent OwnerAddress
HUMAN GENE THERAPY RESEARCH INSTITUTE1415 WOODLAND AVENUE IOWA METHODIST MEDICAL CENTER DES MOINES IA 50309

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Greer, Sheldon B North Miami Beach, FL 7 52
Link, Jr Charles J Clive, IA 11 98

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  • 4 Citation Count
  • A61K Class
  • 9.90 % this patent is cited more than
  • 23 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges344181063626215310053322118113601 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +010020030040050060070080090010001100120013001400150016001700180019002000

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