Radiation enhanced gene therapy for tumors expressing a gene for a viral pyrimidine kinase in the presence of a 5'-halogenated pyrimidine
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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Jan 29, 2002
Issued Date -
N/A
app pub date -
Jul 21, 1999
filing date -
Mar 1, 1995
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention pertains to combination radio therapy of tumors and more specifically to pharmaceutical compositions, and methods of treatment by gene therapy designed to sensitize tumors in animals, notably humans, and render them more susceptible to radiation, thus significantly reducing the amount of radiation required to kill neoplastic cells while at the same time making the radiation far more tissue specific to the tumor site.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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HUMAN GENE THERAPY RESEARCH INSTITUTE | 1415 WOODLAND AVENUE IOWA METHODIST MEDICAL CENTER DES MOINES IA 50309 |
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Greer, Sheldon B | North Miami Beach, FL | 7 | 52 |
# of filed Patents : 7 Total Citations : 52 | |||
Link, Jr Charles J | Clive, IA | 11 | 98 |
# of filed Patents : 11 Total Citations : 98 |
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Patent Citation Ranking
- 4 Citation Count
- A61K Class
- 9.90 % this patent is cited more than
- 23 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text

Legal Events
Date | Code | Event | Description |
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Sep 02, 2019 | LAPS | LAPSE FOR FAILURE TO PAY MAINTENANCE FEES | free format text: PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
Sep 02, 2019 | STCH | INFORMATION ON STATUS: PATENT DISCONTINUATION | free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362 |
Jul 31, 2019 | FP | LAPSED DUE TO FAILURE TO PAY MAINTENANCE FEE | Effective Date: Jul 31, 2019 |
Mar 18, 2019 | FEPP | FEE PAYMENT PROCEDURE | free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: LARGE ENTITY |
Feb 02, 2015 | FPAY | FEE PAYMENT | year of fee payment: 8 |
Jan 24, 2011 | FPAY | FEE PAYMENT | year of fee payment: 4 |
Jul 31, 2007 | I | Issuance | |
Jul 11, 2007 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
Apr 20, 2005 | F | Filing | |
Apr 15, 2005 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:NEWMAN, KENT DAVID;CROCKER, TODD WILLIAM;REEL/FRAME:016492/0388 Owner name: UNIDEN AMERICAN CORPOATION, TEXAS Effective Date: Apr 15, 2005 |
Jul 26, 2002 | PD | Priority Date |

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