Vaccine adjuvants
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United States of America Patent
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Dec 11, 2001
Grant Date -
N/A
app pub date -
Sep 15, 1997
filing date -
Dec 27, 1994
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Abstract
Vaccine adjuvants comprising a sulpholipid polysaccharide in combination with an interface-forming constituent. The invention also provides a method for preparing a vaccine by emulsifying an aqueous solution of an antigen and a sulpholipid polysaccharide. The adjuvants are stable at high temperatures, and are at least as effective as conventional adjuvants. Their local toxicity, i.e. their reactogenicity, is generally lower than that of conventional adjuvants.
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