Mesenchymal stem cells for prevention and treatment of immune responses in transplantation

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United States of America Patent

PATENT NO 6328960
SERIAL NO

09267536

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed is a method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of mesenchymal stem cells effective to reduce or inhibit host rejection of the transplant. The mesenchymal stem cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with mesenchymal stem cells.

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Patent Owner(s)

Patent OwnerAddress
MESOBLAST INTERNATIONAL SÀRLROUTE DE PRE-BOIS 20 MEYRIN 1217

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Klyushnenkova, Elena N Baltimore, MD 5 278
McIntosh, Kevin R Ellicott City, MD 12 893
Mosca, Joseph D Ellicott City, MD 21 946

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