Macromolecular conjugate made using unsaturated aldehydes

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United States of America Patent

PATENT NO 6326136
SERIAL NO

08372810

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Abstract

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Conjugate probes are prepared in a one step process by incubating a macromolecule and a labeling group with an unsaturated polyaldehyde as the conjugating agent. The conjugating agent is capable of bonding virtually any labeling group to a macromolecule. Conjugate probes have been shown to have a high degree of specificity and exhibit a strong signal with minimal background.

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Patent Owner(s)

Patent OwnerAddress
DIGENE CORPORATION1201 CLOPPER ROAD GAITHERSBURG MD 20878

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lazar, James G Bethesda, MD 17 311
Taub, Floyd E Silver Spring, MD 11 108

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