4-phenyl-4-oxo-butanoic acid derivatives with kynurenine-3-hydroxylase inhibiting activity

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United States of America Patent

PATENT NO 6323240
SERIAL NO

09068016

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Abstract

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4-phenyl-4-oxo-butanoic acid derivatives for use in the treatment of the human or animal body by therepy; particularly as kynurenine-3-hydroxylase inhibitors, in the prevention and/or treatment of a neurodegenerative disease wherein the inhibition of such an enyzme is needed. The present invention further comprises a selected class of the above mentioned 4-phenyl-4-oxo-butanoic acid derivatives, their pharmaceutically acceptable salts, a process for their preparation and pharmaceutical compositions containing them.

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Patent Owner(s)

Patent OwnerAddress
PHARMACIA & UPJOHN S P AVIA ROBERT KOCH 1/2 MILAN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Giordani, Antonio Pavia, IT 38 126
Pevarello, Paolo Pavia, IT 65 1038
Speciale, Carmela Nerviano, IT 14 51
Varasi, Mario Milan, IT 86 1096

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