Anti-viral guanosine-rich oligonucleotides and method of treating HIV
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United States of America Patent
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Nov 27, 2001
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N/A
app pub date -
Jul 17, 1996
filing date -
Apr 23, 1993
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Expired
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Abstract
A method and compositions for treating viral infection in vitro and in vivo using a guanosine-rich oligonucleotide. The oligonucleotides have sufficient guanosine to form a guanosine tetrad. Also provided are oligonucleotides of at least two runs of at least two guanosines. Also provided are guanosine-rich oligonucleotides and methods for treating viral infections in humans, and a method for designing guanosine-rich oligonucleotides having anti-viral activity and integrase inhibition activity.
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