Method of enhancing insulin action

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United States of America Patent

PATENT NO 6316458
SERIAL NO

09557318

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A category of hydroxyalkyl-substituted xanthines are useful in treating patients suffering from disorders associated with impaired glucose metabolism or impaired insulin function. Use of these compounds, for example, restores insulin responsiveness in otherwise insulin-resistant Type 2 diabetic patients, thus reducing elevated blood glucose levels. The subject compounds also act to restore certain defects of lipid metabolism and to enhance the effects of insulin in general. Insulin-enhancing compositions and methods of treating disorders of glucose metabolism are provided.

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Patent Owner(s)

Patent OwnerAddress
CITY OF HOPE1500 EAST DUARTE ROAD DUARTE CA 91010-3000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Balon, Thomas W Covina, CA 1 16
Nadler, Jerry L Charlottesville, VA 26 226
Yamaguchi, Yoko Glendora, CA 41 729

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