Detection of reverse transcriptase by DNA hybridization assay
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United States of America Patent
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Nov 13, 2001
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app pub date -
Jul 14, 1992
filing date -
Jan 15, 1992
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Abstract
A method for detecting reverse transcriptase (RT), utilizing RT-catalyzed generation of cDNA complementary to an RNA template and detecting cDNA in a DNA hybridization reaction, is provided. Also provided is a method for detecting and/or quantitating drug resistance of reverse transcriptase in a sample and a method for evaluating ability of a compound to inhibit reverse transcriptase activity.
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