2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase, 19-hydroxylase inhibitors and methods of their use in the treatment of estrogen mediated disorders

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United States of America Patent

PATENT NO 6313161
SERIAL NO

09426993

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Abstract

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The present invention is directed to a method of using a certain compounds which are 2,19-methyleneoxy or 2,19 methylenethio bridged steroids, and related steroidal compounds as inhibitors of the enzyme steroid aromatase, 19-hydroxylase and as treatment for various estrogen dependent/mediated disorders including hormonal dependent breast cancer.

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Patent Owner(s)

Patent OwnerAddress
MERRELL PHARMACEUTICALS INC2110 EAST GALBRAITH ROAD CINCINNATI OH 45215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burkhart, Joseph P West Chester, OH 30 176
Johnston, J O'Neal Milford, OH 15 52
Peet, Norton P Cincinnati, OH 90 515

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