Overhauser magnetic resonance imaging (ORMI) method comprising ex vivo polarization of a magnetic resonance (MR) imaging agent
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Oct 30, 2001
Issued Date -
N/A
app pub date -
Dec 13, 1999
filing date -
Jun 19, 1997
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
This invention provides a method of MR investigation of a sample, the method comprising: (i) placing in a uniform magnetic field a composition comprising an OMRI contrast agent and an MR imaging agent containing nuclei (MR imaging nuclei) capable of emitting magnetic resonance signals (e.g. the primary magnetic field B.sub.0) and capable of exhibiting a T.sub.1 relaxation time of 6 s or more (at 37.degree. C. in D.sub.2 O in a field of 7T); (ii) exposing the composition to a first radiation of a frequency selected to excite electron spin transitions in the OMRI contrast agent; (iii) optionally but preferably separating the whole, substantially the whole, or a portion of said OMRI contrast agent from said MR imaging agent; (iv) administering said MR imaging agent to said sample, (v) exposing the sample to a second radiation of a frequency selected to excite nuclear spin transitions; (vi) detecting magnetic resonance signals from the sample; and (vii) optionally, generating an image or dynamic flow data from the detected signals.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully