Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use
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United States of America Patent
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Oct 23, 2001
Issued Date -
N/A
app pub date -
Jun 21, 2000
filing date -
Mar 25, 1997
priority date (Note) -
Expired
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Abstract
The present invention is directed to compound of the formula I: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R .sub.5, X, Y, and ##STR2## are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.
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