Time-release laminar pharmaceutical composition
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United States of America Patent
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-
Oct 23, 2001
Grant Date -
N/A
app pub date -
Apr 13, 1998
filing date -
Apr 16, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A time-release laminar pharmaceutical composition, comprised of rolled or folded layers of a polymer film, that contain a pharmaceutically active substance, in which the outer surface area of the polymer film which contains the active substance, and which is accessible to the digestive juices, amounts to at most 25% of the entire surface area in the rolled or folded state, and the rolled or folded layers adhere to one another in such a way that the laminar form of medication maintains its rolled or folded form for a period of at least one hour in the release test according to USP 23, Method A, apparatus 2, at 37.degree. C. and 50 rpm, in artificial gastric juice, and at least 30% of the active substance contained in it is released in the rolled or folded state.
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