pH-modified biocompatible monomer and polymer compositions
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United States of America Patent
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Oct 23, 2001
Issued Date -
N/A
app pub date -
Jun 7, 2000
filing date -
Jun 28, 1994
priority date (Note) -
Expired
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Abstract
The pH-modified monomer and polymer compositions are useful as biomedical and surgical adhesives, sealants, implants and bioactive agent release carriers or matrices. They comprise a monomer or polymer; and an effective amount of an acidic or basic pH modifier effective to modify the pH of an immediate in vivo environment of the composition to a pH range at which the polymer biodegrades at a different rate than at physiologic pH. The invention also relates to in vivo applications in which surfaces are joined or treated with such pH-modified biocompatible compositions.
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