Rapid flow-through binding assay apparatus and method therefor
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United States of America Patent
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Oct 16, 2001
Issued Date -
N/A
app pub date -
Jun 29, 1998
filing date -
Jun 27, 1997
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Expired
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Abstract
The invention includes assay cassettes that can be employed during rapid flow-through binding assays. The assay cassettes can be disposable units suitable for one-time use and readily assembled to include a filter membrane carried between an upper plate and a lower plate. A pattern of channels can extend through the top plate to allow a fluid sample to be applied through the top plate and onto the filter. The bottom plate can include a plurality of channels that are aligned with the channel of the top plate and which will allow a negative pressure to be applied to the underside of the filter membrane to draw the sample through the filter. In one embodiment, the cassette includes a frangible section that allows the cassette to be divided into a first and second component.
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