Specific binding assays
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United States of America Patent
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Sep 25, 2001
Grant Date -
N/A
app pub date -
May 22, 1997
filing date -
May 23, 1996
priority date (Note) -
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Abstract
Disclosed is a method of detecting the presence of an analyte of interest in a sample, the method comprising the steps of: providing a binding partner reversibly immobilised on a solid support, said binding partner having binding specificity for the analyte; contacting the sample with the solid support; specifically displacing the binding partner from the solid support in response to the presence of the analyte of interest in the sample, said displacement causing a reduction in the mass of material immobilised on the solid support, thereby generating a detectable change in a mass-dependent property of the solid support; and detecting said change. Also disclosed is an assay device for performing the method of the invention.
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