Replication genes and gene products from small cryptic plasmids and methods for constructing controlled-replication plasmid vectors
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United States of America Patent
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Sep 25, 2001
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N/A
app pub date -
Mar 13, 1998
filing date -
Mar 14, 1997
priority date (Note) -
Expired
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Abstract
The replication genes of small cryptic plasmids are isolated and used to construct controlled-replication plasmid vectors with the wide range of copy numbers controlled by defined helper plasmids. Controlled-replication vectors (RAMP vectors) can reach very high level of plasmid replication, which is not lethal to host unlike runaway replication vectors.
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