Composition and methods for modulating the length of telomeres
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United States of America Patent
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Sep 25, 2001
Grant Date -
N/A
app pub date -
Feb 25, 1999
filing date -
Jul 1, 1996
priority date (Note) -
Expired
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Abstract
The present invention relates to the length of telomeres and the role of hnRNP A1, UP1 or derivatives thereon. More particularly, the present invention relates to hnRNP A1, UP1 or derivatives thereof to maintain or alter the length of telomeres in cells. The present invention also relates to methods and compositions for increasing or decreasing the proliferative capacity of cells and to delay or precipitate the onset of senescence The invention further relates to hnRNP A1 or UP1 or derivatives thereof as pharmaceutical, therapeutic and diagnostic reagents.
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