Nimesulide topical formulations in the form of liquid crystals
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United States of America Patent
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Sep 11, 2001
Grant Date -
N/A
app pub date -
Aug 4, 1999
filing date -
Feb 25, 1997
priority date (Note) -
Expired
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Abstract
Nimesulide topical formulations are provided in the form of liquid crystals. The emulsifier cetylstearyl glycoside is used, and constituents of the lipid phase such as caprylic/capric triglycerides and jojoba oil, consistence factors such as cetylstearyl alcohol. Also disclosed is a process for the preparation thereof. The formulations have advantages such as higher stability, better release and absorption of nimesulide, and a higher bioavailability of the active ingredient.
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