Optimally stabilized microgranule comprising 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazole derivative
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United States of America Patent
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Aug 28, 2001
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N/A
app pub date -
May 3, 1999
filing date -
Dec 29, 1998
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Abstract
The present invention relates to a microgranule prepared by using an alkali compound as a stabilizer for a 5-pyrrolyl-2-pyridylmethylsulfinylbenzimidazole derivative having the following formula (1), which is a very effective antiulcerative but highly unstable under acidic conditions, and by using a water-soluble polymer as a binding agent. ##STR1## in which X, R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are defined as described in the specification.
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