Assays and reagents for identifying anti-fungal agents, and uses related thereto
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United States of America Patent
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Aug 21, 2001
Issued Date -
N/A
app pub date -
Apr 23, 1997
filing date -
Apr 11, 1996
priority date (Note) -
Expired
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Abstract
The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis. Another aspect of the present invention relates to novel Candida genes and gene products.
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