Method of targeting a specific location in a body using phospholipid and cholesterol liposomes which encapsulate an agent
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Aug 14, 2001
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Mar 30, 1982
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Micellular particles such as small unilamellar vesicles of less than 2000 A.degree. loaded with .sup.111 In are administered to BALB/c mice in which EMT6 tumors had been induced. Whole body scintographs of the mice to which either neutral or positively or negatively charged vesicles had been administered show a substantial quantity of the vesicle entrapped .sup.111 In localized in the tumor. Blocking of macrophages in the liver and spleen by first administering unlabeled, aminomannose substituted vesicles before administration of the labeled vesicles increases uptake of the .sup.111 In labeled vesicles in the tumor.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully