3'-Deoxyribonucleotide derivatives
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United States of America Patent
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Jul 24, 2001
Grant Date -
N/A
app pub date -
Mar 5, 1999
filing date -
Jul 7, 1997
priority date (Note) -
Expired
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Abstract
Disclosed are 3'-deoxyribonucleotide derivatives represented by the following general formula [I]: Q--V--(CH.sub.2).sub.n --NH--R [I] wherein Q represents a 3'-deoxyribonucleotide residue, n represents an integer not less than 4, V represents --C.ident.C-- or --CH.dbd.CH--, and R represents a fluorescent group. The above 3'-deoxyribonucleotide derivatives are derivatives with improved rates for incorporation using RNA polymerases, which are useful as terminators in the DNA sequence determination methods utilizing RNA polymerases.
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