Nucleic acid molecules comprising a neocentromere
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United States of America Patent
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Jul 24, 2001
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N/A
app pub date -
May 13, 1998
filing date -
May 13, 1997
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Abstract
The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
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