Transcription therapy for cancers
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United States of America Patent
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Jul 17, 2001
Grant Date -
N/A
app pub date -
Sep 18, 1998
filing date -
Jan 23, 1998
priority date (Note) -
Expired
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Abstract
The present invention provides method of treating a neoplastic condition in an individual, comprising the step of administering to said individual a pharmacologically effective dose of a retinoic acid and/or an inhibitor of histone deacetylase. Also provided is a pharmaceutical composition, comprising a retinoic acid, an inhibitor of histone deacetylase and a pharmaceutically acceptable carrier. Further provided is a method of inducing terminal differentiation of tumor cells in a tumor in an individual in need of such treatment, comprising the step of administering to said individual a pharmacologically effective dose of a retinoic acid and/or an inhibitor of histone deacetylase.
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