Compounds that inhibit the binding of integrins to their receptors
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United States of America Patent
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Jul 17, 2001
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N/A
app pub date -
Oct 14, 1999
filing date -
Apr 16, 1998
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Abstract
A method for the inhibition of the binding of .alpha..sub.4.beta..sub.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions thereof; and the use of the compounds either as above, or in formulations for the control or prevention of diseases states in which .alpha..sub.4.beta..sub.1 is involved.
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