Hydrophobic preparations containing medium chain monoglycerides
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United States of America Patent
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Jul 10, 2001
Grant Date -
N/A
app pub date -
Dec 22, 1998
filing date -
Jul 2, 1996
priority date (Note) -
Expired
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Abstract
Hydrophobic preparations which are useful as, among other things, pharmaceutical delivery systems comprise: (i) an oil phase comprising one or more medium chain monoglycerides, such as Akoline MCM.TM.; (ii) at least one amphiphile, preferably including a phospholipid such as phosphatidyl choline; and (iii) a hydrophilic species, which may be a protein such as insulin or calcitonin or another macromolecule, solubilized or otherwise dispersed in the one or more glycerides. The hydrophilic species is one that is not normally soluble in the glycerides.
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