Highly sensitive fluoroassay

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United States of America Patent

PATENT NO 6255048
SERIAL NO

09011223

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Abstract

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This invention provides fluoroassay which comprises labeling analyte molecules with a fluorescent material having a nucleic acid portion stained with a sufficient number of fluorochrome molecules so as to be measurable as fluorescent spots, and a reactive group binding to the analyte molecule specifically, immobilizing the labeled analyte on a solid phase, and counting the number of fluorescent spots. The nucleic acid portion of the fluorescent labeling material is a double-stranded or single-stranded nucleic acid, and the staining with the fluorochrome molecules is performed with intercalating type, minor groove binding type, or covalently binding to the nucleic acid type.

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Patent Owner(s)

Patent OwnerAddress
LABORATORY OF MOLECULAR BIOPHOTONICSHAMAKITA-SHI SHIZUOKA-KEN 434

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hosoi, Shigeru Hamakita, JP 6 119
Kadouchi, Sachiko Hamakita, JP 1 3
Kojima, Makiko Matsumoto, JP 7 8

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