Chromosomally-encoded membrane protein of borrelia burgdorferi
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United States of America Patent
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Jun 19, 2001
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app pub date -
Sep 27, 1994
filing date -
Sep 27, 1994
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Abstract
The present invention relates to an isolated membrane protein or polypeptide encoded by chromosomal DNA of Borrelia burgdorferi (e.g., BmpC). This protein is encoded by a DNA molecule (e.g., bmpC) and is useful in vaccines to prevent infection by Borrelia burgdorferi, while antibodies raised against this protein can be employed in passively immunizing those already infected by the organism. Both these proteins and antibodies may be utilized in diagnostic assays to detect Borrelia burgdorferi and immune response in tissue or body fluids. Likewise, the DNA molecule can be used for detection of this organism.
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