Method for producing optically active phenylpropionic acid derivative
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United States of America Patent
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May 29, 2001
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N/A
app pub date -
Dec 7, 1999
filing date -
Feb 16, 1998
priority date (Note) -
Expired
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Abstract
Optically active N-(S-2-acetylthiomethyl-1-oxo-3-phenylpropyl)-glycine benzyl ester useful as an enkephalin inhibitory agent or ACE inhibitory agent can be produced at low cost in an industrial manner, by a method comprising subjecting optically active 2-hydroxymethyl-3-phenylpropionic acid and glycine benzyl ester to condensation to subsequently convert the hydroxyl group into an elimination group, and substituting the elimination group with an acetylthio group.
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