Immunostimulatory nucleic acid molecules

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United States of America Patent

PATENT NO 6239116
SERIAL NO

08960774

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Abstract

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Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful a synthetic adjuvant.

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Patent Owner(s)

Patent OwnerAddress
HEALTH AND HUMAN SERVICES DEPARTMENT OF UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY THEBUILDING 29A 3D10 BETHESDA MD 20892

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kline, Joel N Iowa City, IA 11 744
Krieg, Arthur M Iowa City, IA 154 11149

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  • 443 Citation Count
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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges1111 - 2061 - 7000.050.10.150.20.250.30.350.40.450.50.550.60.650.70.750.80.850.90.9511.05

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