IKK-.alpha. proteins, nucleic acids and methods
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United States of America Patent
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May 22, 2001
Grant Date -
N/A
app pub date -
Feb 13, 1998
filing date -
Jul 1, 1997
priority date (Note) -
Expired
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Abstract
The invention provides methods and compositions relating to an I.kappa.B kinase, IKK-.alpha., and related nucleic acids. The polypeptides may be produced recombinantly from transformed host cells from the disclosed IKK-.alpha. encoding nucleic acids or purified from human cells. The invention provides isolated IKK-.alpha. hybridization probes and primers capable of specifically hybridizing with the disclosed IKK-.alpha. genes, IKK-.alpha.-specific binding agents such as specific antibodies, and methods of making and using the subject compositions in diagnosis, therapy and in the biopharmaceutical industry.
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