Monitoring of gene expression by detecting hybridization to nucleic acid arrays using anti-heteronucleic acid antibodies
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United States of America Patent
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May 15, 2001
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N/A
app pub date -
Jan 22, 1999
filing date -
Jan 22, 1999
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Expired
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Abstract
The present invention relates to anti-heteronucleic acid antibodies and their uses for detection of RNA-DNA duplexes on arrays. The invention provides a method for detection of total cellular RNA hybridization on microarrays, thus obviating the need for isolation of the poly(A).sup.+ fraction.
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