Aromatic esters of camptothecins and methods to treat cancers
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United States of America Patent
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May 8, 2001
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Aug 3, 1999
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Aug 3, 1999
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Abstract
Aromatic camptothecin ester compounds having the formula: ##STR1## are described as well as formulations containing the compounds. Methods of treating cancer and/or tumors are also disclosed.
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Family
Country | kind | publication No. | Filing Date | Type | Sub-Type |
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- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
- CAO PHARMACEUTICALS INC.;THE CHRISTUS STEHLIN FOUNDATION FOR CANCER RESEARCH
International Classification(s)
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
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Cao, Zhisong | Friendswood, TX | 17 | 191 |
# of filed Patents : 17 Total Citations : 191 | |||
Giovanella, Beppino C | Houston, TX | 24 | 275 |
# of filed Patents : 24 Total Citations : 275 |
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- 7 Citation Count
- A61K Class
- 9.78 % this patent is cited more than
- 24 Age
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Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
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Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text
US Patent Application No: 10993676
Signal processing method and apparatus
Abstract
A method and apparatus for estimating the frequency of a dominant periodic component in an input signal by modelling the input signal using auto-regressive models of several different orders to generate candidate frequencies for the periodic component, generating synthetic sinusoidal signals of each of the candidate frequencies, and calculating the cross-correlation of the synthetic signals with the original signal. The frequency of whichever of the synthetic signals has the highest cross-correlation with the original signal is taken as the estimate of the frequency for the dominant periodic component of the input signal. The method may be applied to any noisy signal which has a suspected periodic component, for example physiological signals such as photoplethysmogram signals, and in the estimation of heart rate and breathing rate from such physiological signals.
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