Process for the purification of 11.beta.-21-dihydroxy-2'-methyl-5'.beta.H-pregna-1,4-dieno[17,16-D]oxazole-3,20-dione
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United States of America Patent
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May 8, 2001
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app pub date -
Aug 7, 1998
filing date -
Feb 16, 1996
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Abstract
Process for preparing the compound 11.beta.-21-dihydroxy-2'-methyl-5'.beta.H-pregna-1,4-dieno[17,16-d]oxazoline-3,20-dione of formula (I): ##STR1## which comprises adsorbing said compound, contained into an aqueous solution resulting from fermentation broths or process streams, on an adsorbent polymeric resin having a styrenic or acrylic matrix and subsequently desorbing the said compound by eluting the resin with suitable mixture of water with a water-miscible organic solvent.
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