Method of detecting solid cancer cells and tissue atypia and method of testing tissues for use in bone marrow transplantation and peripheral blood stem cell transplantation
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United States of America Patent
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May 1, 2001
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app pub date -
Jun 26, 1998
filing date -
Apr 16, 1996
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Abstract
The invention provides a method of detecting solid cancer cells which comprises determining the level of expression of WT1 gene in a test tissue, a method of detecting the atypia of a tissue which comprises determining the level of expression of WT1 gene in the tissue, and a method of testing a graft material tissue for bone marrow or peripheral blood stem cell transplantation which comprises determining the level of expression of WT1 gene in a CD34.sup.- cell fraction of the tissue to detect leukemic cells and solid cancer cells in the tissue.
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