Tricyclic compounds having activity specific for integrins, particularly alphanubeta3 integrins, method for preparing same, intermediates therefor, use of said compounds as drugs, and pharmaceutical compositions containing same

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United States of America Patent

PATENT NO 6221907
SERIAL NO

09155063

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The subject of the invention is the products of formula (I): ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and G are as defined in the description, the dotted lines represent an optional second bond, as well as the addition salts with acids and bases and the esters, their preparation process and the intermediates of this process, their use as medicines and the pharmaceutical compositions containing them.

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Patent Owner(s)

Patent OwnerAddress
HOECHST MARION ROUSSEL92800 PUTEAUX
GENENTECH460 POPINT SAN BRUNO BOULEVARD SAN FRANCISCO CA 94080

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bernard, Serge Le Plessis Belleville, FR 63 373
Bodary, Sarah C San Bruno, CA 29 358
Carniato, Denis Marcoussis, FR 56 250
Gadek, Thomas R Oakland, CA 36 1667
Gourvest, Jean-Francois Claye-Souilly, FR 38 225
Knolle, Jochen Kriftel, DE 68 504
McDowell, Robert S San Francisco, CA 40 533
Pitti, Robert M El Cerrito, CA 17 158
Stilz, Hans-Ulrich Frankfurt am Main, DE 6 36
Teutsch, Jean-Georges Pantin, FR 51 641
Wehner, Volkmar Sandberg, DE 73 535

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