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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
HOECHST AKTIENGESELLSCHAFT	65926 FRANKFURT AM MAIN

International Classification(s)

• A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
• C07K:PEPTIDES

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Ertl, Johann	Bremthal, DE	8	154
# of filed Patents : 8 Total Citations : 154
Geisen, Karl	Frankfurt, DE	33	492
# of filed Patents : 33 Total Citations : 492
Habermann, Paul	Eppstein, DE	46	702
# of filed Patents : 46 Total Citations : 702
Seipke, Gerhard	Hofheim, DE	16	346
# of filed Patents : 16 Total Citations : 346

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Patent Citation Ranking

• 28 Citation Count
• A61K Class

• 81.75 % this patent is cited more than
• 24 Age

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Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

Full Text

US Patent No: 6221837

Insulin derivatives with increased zinc binding

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Abstract

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Insulin derivatives with increased zinc binding ##STR1## where Z is a histidine residue or a peptide having 2 to 35 genetically encodable amino acid residues, having 1 to 5 histidine residues, are suitable for the production of pharmaceutical preparations for the treatment of diabetes. Insulins of the formula I form complexes with zinc.sup.++, comprising an insulin hexamer and approximately 5 to 9 mol of zinc.sup.++ per hexamer.

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Description

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Claims

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