Combination pharmaceutical composition and associated methods
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United States of America Patent
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Apr 24, 2001
Grant Date -
N/A
app pub date -
Aug 25, 1997
filing date -
Aug 25, 1997
priority date (Note) -
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Abstract
A novel pharmaceutical combination is described, together with a method of making the same and a method of treating hypertensive patients using the same, wherein (1) the pharmaceutically active antihypertensive agent and citric acid and (2) the pharmaceutically active antikaliuretic agent and a nonionic surfactant are mixed, either together or separately, to form an essentially homogenous combination composition, and only thereafter blending with excipients to form the novel combination composition in solid dosage form.
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