Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Apr 17, 2001
Issued Date -
N/A
app pub date -
Feb 3, 2000
filing date -
Jan 26, 1996
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
Process for preparing intermediates of formula (III) ##STR1## wherein Y.sup.1 is acyloxy, wherein acyl is of the formula R--C(O)--, wherein R is alkyl of 1-6 carbon atoms, Y.sup.2 is aralkyloxy, and Z is benzoyloxy or acyloxy, wherein acyl is as defined above. Intermediates of formula (III) are useful in a novel process for preparing the mono-L-valine ester of 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol (ganciclovir). The mono-L-valine ester of ganciclovir and its pharmaceutically acceptable salts are of value as antiviral agents with improved absorption.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully