Sugar-chain synthetase and process for producing the same
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United States of America Patent
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Apr 17, 2001
Grant Date -
N/A
app pub date -
Aug 28, 1998
filing date -
Dec 24, 1993
priority date (Note) -
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Abstract
Novel GalNAc.alpha.2,6-sialyltransferases P-B1 and P-B3; GalNAc.alpha.2,6-sialyltransferase genes encoding the above GalNAc.alpha.2,6-sialyltransferases P-B1 and P-B3; and an extracellularly releasable protein catalyzing GalNAc.alpha.2,6-sialic acid transfer which comprises a polypeptide portion as being an active domain of the GalNAc.alpha.2,6-sialyltransferase P-B1 or P-B3 together with a signal peptide are provided. Also provided is a process for preparing a sialyltransferases which enables efficient recovery of a sialyltransferase expressed in a large quantity in microorganisms.
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