Biotransformation of fatty substrates

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United States of America Patent

PATENT NO 6218158
SERIAL NO

07896705

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Abstract

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This invention relates to a process for enzymic oxidation of a fatty acid to produce an oxidation product in the presence of water and oxygen wherein the fatty acid, water and enzyme for the oxidation are substantially uniformly distributed throughout a porous bed of solid support material in the substantial absence of a continuous liquid phase, oxygen is passed through the porous bed and the oxidation product is recovered from the porous bed. The invention is of particular value for production of methyl ketones from saturated fatty acids. Apparatus for carrying out the process is also novel and includes a sealable vessel that can contain a porous bed of solid support material, a gas inlet for supplying oxygenating gas to the reactor, a gas outlet, passage means defining a plurality of upwardly extending passages that can open along their length into the bed and that communicate with the inlet and that are preferably spaced 5 to 20 cm (preferably 5 to 15 cm) apart, and means for forcing oxygenating gas through the inlet and along and out from the passages and into the bed.

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Patent Owner(s)

Patent OwnerAddress
BUSH BOAKE ALLEN LIMITEDBLACKHORSE ROAD A BRITISH COMPANY WALTHAMSTON LONDON E17 5QP

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Humphrey, Anthony Martin Chorleywood, GB 2 3
Kinderlerer, Judith L Sheffield, GB 3 7
Skill, Bridget Ann Leigh-On-Sea, GB 2 3

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