Method of detection of carcinogenic human papillomavirus
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United States of America Patent
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Apr 17, 2001
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N/A
app pub date -
Dec 30, 1997
filing date -
Feb 26, 1987
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Expired
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Abstract
High risk carcinogenic human types 16, 18 and 33 are distinguished from low risk human papillomavirus types 6 and 11 in a sample of human cervical tissue. A selected characteristic portion of the E6 region of the virus defined by specific oligonucleotide primers is amplified using a polymerase chain reaction. The presence or absence of the characteristic portion of the E6 region is detected by gel electrophoresis or using a labeled oligonucleotide probe.
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