Method and apparatus for preparation of chiral beta amino acids using penicilln G acylase
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United States of America Patent
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Apr 10, 2001
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N/A
app pub date -
May 1, 1998
filing date -
May 1, 1997
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Expired
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Abstract
A method for preparing a chiral beta amino acid or its corresponding esters which comprises contacting a racemic beta amino acid, an acyl donor and Penicillin G acylase enzyme under conditions appropriate to stereoselectively acylate one enantiomer of the racemic beta amino acid to its corresponding N-acylated derivative whereby the opposite enantiomer of the beta amino acid is retained in enantiomerically enriched form.
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