Lysosomal enzyme-cleavable antitumor drug conjugates

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United States of America Patent

PATENT NO 6214345
SERIAL NO

08062366

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Abstract

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The present invention relates to drug-ligand conjugates wherein the drug is linked to the ligand through a protein peptide linker and a connector, a process for the preparation of the conjugates, method of controlling the growth of undesirable cells, pharmaceutical compositions, and intermediates thereof.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS SQUIBB COMPANYROUTE 206 & PROVINCE LINE ROAD PRINCETON NJ 08543

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dubowchik, Gene Michael Middlefield, CT 2 578
Firestone, Raymond Armand New Haven, CT 1 577

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